خاموش کردن ژن bcr-abl توسط مورفولینوالیگو آنتی سنس
thesis
- وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی
- author محمود حریریان
- adviser سعید کاویانی مسعود سلیمانی
- Number of pages: First 15 pages
- publication year 1387
abstract
چکیده ندارد.
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Aberrant tyrosine kinase activity plays a critical role in many hematologic disorders, including chronic myeloid leukemia characterized by the constitutive activity of BCR-ABL. ABL therefore represents a crucial target for new therapeutic strategies. Here, we summarize the molecular pathways that are abnormally activated by the oncoprotein. Such pathways may provide additional opportunities to ...
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract Aberrant Tyrosine kinase (TK) activity is critical in many hematological disorders, including chronic myeloid leukemia (CML) characterized by the constitutive activity of BCR-ABL. ABL therefore represented a crucial target for new therapeutic strategies. The molecular pathways abnormal...
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document type: thesis
وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی
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